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These investigations consistently indicate a lack of evidence supporting a causal relationship between elevated serum urate levels and the risk of developing type 2 diabetes mellitus, coronary heart disease, ischemic stroke, and heart failure

doi:10.1007/s13277-012-0595-9 Huang W, Wang W, Zhou M, Zhang X (2013) Association of single-nucleotide polymorphism rs4236601 near caveolin 1 and 2 with primary open-angle glaucoma: a meta-analysis

He points to some small studies from his clinic, for example with the popular BPC-157, as evidence of safety

Expression of NOS is elevated in patients with endometriosis, and a common polymorphism of exon 7 at nucleotide 894 in the endothelial NOS gene may be associated with endometriosis [135]

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