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It is currently MHRA and NICE approved for treating bladder pain (interstitial cystitis of the bladder) , so it can be repurposed as an osteoarthritis treatment
DSIP has been evaluated in experimental frameworks examining stress-induced changes in neuroendocrine signaling
Common side effects Injection-site reactions: mild redness, tenderness, swelling, occasional bruising - usually resolve within hours Skin flushing / warmth - brief, related to vasodilation Transient fatigue in the first 12 weeks of intensive protocols Mild headache - usually dose-related Higher-dose theoretical concerns Copper accumulation - each 2 mg injection adds roughly 0.03 mg of elemental copper, trivial next to the 0.92.2 mg from a normal diet
Vitamin B12 is generally considered the most effective for sciatic nerve pain as it regenerates and repairs nerves in the body
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