In a xenograft model, ASAH2 inhibition resulted in elevated ceramide levels, reduced proliferation, and delayed tumor growth, confirming the functional requirement of neutral ceramidase in colon cancer control and progression [52]
& Vos, J
Medicinal Research Reviews , 43 (6), 20252085
MG132, attenuates the retinal vascular injury through the upregulation of Nrf2 expression
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