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These observations can be translated into normal mice by augmenting their LLF glutathione thru inhibition of GGT enzyme activity ( in vivo as shown in previous human clinical trials as a cancer therapeutic ( in vivo and has been utilized in a renal ischemia/reperfusion injury model in rats (Yamamoto et al., 2011)

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(4) Intracellular TAAR1 activation: Elevated cytoplasmic tyramine activates trace amine-associated receptor 1 (TAAR1), promoting signaling pathways that result in phosphorylation of the NET transporter, modify transporter function to cause it to switch to reverse transport mode (rNET)

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