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Matsumoto M, Sasaki N, Tsujino T, Akahori H, Naito Y, Masuyama T

The altered gastric emptying and potential changes in food intake associated with semaglutide therapy may affect the absorption and metabolism of warfarin, potentially leading to fluctuations in international normalized ratio values

Financial support and sponsorship: Supported in part by NIH grant R01 AG057381

Its overactivation disrupts nicotinamide metabolism, reduces NAD+ levels, promotes hepatic lipid accumulation and lipotoxicity, and represents an important therapeutic target for hepatic metabolic disorders

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