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Science Translational Medicine , 13(600), eabc8014

Archived from the original on 1 May 2024

Ramos-Jimnez A, Hernndez-Torres RP, Hernndez-Ontiveros DA, Ortiz-Ortiz M, Lpez-Fregoso RJ, Martnez-Sanz JM, Rodrguez-Uribe G, Hernndez-Lepe MA

Interestingly, these seemingly dichotomous effects of E2 on intracellular bioenergetics could be a result of differential receptor activation, as E2 was found to inhibit F0F1-ATP synthase activity via non-genomic mechanisms in a human osteoclastic cell line (FLG 29.1 cells) (200)