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Through neural, immune, endocrine, and metabolic signaling pathways, the gut microbiome can influence brain physiology, while the brain can in turn modulate gut microbial composition via stress hormones and autonomic innervation [11, 12]

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Inhibition of autophagy in cells under high-fat conditions aggravates atherosclerosis, and iron accumulation often occurs in plaques, which may be caused by dysregulated mitophagy and the abrogation of the fragile metabolic balance in foam cells [225, 226]

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Tissue Repair: By reducing inflammation, it may promote more effective healing in injured tissues