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Neu SC, Pa J, Kukull W, et al

Weight loss in this period averages 2 to 4 pounds

11,12 Inflammation is a series of defensive responses to stimuli that may be related to viral or bacterial infections, autoimmune diseases and tumors

Dysbiosis, through the lack of appropriate immunoregulatory and barrier factors, such as, e.g., short-chain fatty acids, causes inappropriate activation of the immune system, resulting in epithelial inflammation, epithelial barrier damage and disease development [55, 57,58,59,60,61]

However, there are still several unresolved questions regarding their mechanism of action, interactions with other proteins, and their influence on plant development and stress-responsive signaling