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Further work is needed to clarify whether strains differ in how they impact oxidative status

Unlike E3 and E4 mice, in E2 mice plasma acylcarnitines, particularly LCAs, remained elevated with age and overall higher than in other genotypes regardless of age

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It is used in research settings to investigate NNMT-dependent metabolic pathways, including relationships to NAD+ metabolism, cellular energy regulation, and metabolic homeostasis in experimental models

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Hierarchical status predicts behavioral vulnerability and nucleus accumbens metabolic profile following chronic social defeat stress