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The most common features found among the ensembles correspond to aromatic interactions, including those caused by the residues Trp-86, Tyr-341, Tyr-337, Tyr-124, Tyr-72, and Trp-286 (Figure 5)

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Chlorambucil is an effective alkylating agent used in cancer treatment, targeting DNA replication and inducing apoptosis

In the case of organic compounds, biotransformation steps are often necessary and their nature, mechanism(s), responsible enzymes and related polymorphisms are well characterized and the respective role in determining individual sensitivity to the effects of exposure at different levels is a well-established field of investigation

The FDA hasn't approved the use of copper peptides for injectables