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2024;68: e230197 Assessment of thiol-disulfide and glutathione homeostasis after levothyroxine replacement in individuals with autoimmune or nonautoimmune hypothyroidism DOI: 10.20945/2359-4292-2023-0197 ABSTRACT Objective Thyroid hormones are known to affect the biosynthesis and degradation of antioxidant compounds, suggesting a possible link between hypothyroidism and oxidative stress

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For instance, in a mouse model of muscle atrophy characterized by systemic iron overload and heightened lipid peroxidation, deferiprone treatment further reduced mitochondrial iron-containing proteins without altering ferritin levels [41]

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