In particular, skeletal muscle weight, needed for posture and locomotion, is a relatively constant 45% of body weight among mammals
Amino Acids 41, 159171, 10.1007/s00726-010-0571-x (2011)
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The importance of these pathways in yielding pyruvate in the absence of pyruvate kinase is further supported by many reports showing that inhibition of this enzyme does not lead to a proportional decrease in pyruvate/lactate formation, reviewed in ref
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