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The FDA guidelines (for women, which clinicians also follow for men) say no more than one dose in 24 hours, and no more than 8 doses per month

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It is advised to increase the dosage to 600 mcg/d during pregnancy

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doi: 10.3109/14767058.2011.599081

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Dexmedetomidine: review, update, and future considerations of paediatric perioperative and periprocedural applications and limitations

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Can supplements be given to children

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