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At one end of the spectrum, inadequate antioxidant defenses permit unchecked OS, leading to lipid peroxidation of sperm membranes, DNA fragmentation, and impaired sperm motility and viability
Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A et al (2020) Cysteine depletion induces pancreatic tumor ferroptosis in mice
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Fer-1 liposome eye drops can inhibit corneal opacity and increase bioavailability fivefold in a rabbit corneal alkali burn model, which indicates that agents that target ferroptosis have the potential for clinical translation and the treatment of ocular diseases
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