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1 , 2 These mutations result in the substitution of single amino acid residue, E6 to V in sickle hemoglobin (HbS) allele S , or E6 to K in HbC

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Running BPC-157 continuously for months without a break is not supported by any published protocol

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An analysis based on elevated total cysteine (above the median) and low GSH-T (below the median) showed a similar result on GlyNAC efficacy in this subpopulation (medians, V2 = 817.7, V4 = 859.3 mg/L per %Ht, p -value = 0.015) (Supplementary Figure S3)