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doi: 10.1046/j.1432-1327.1999.00630.x 159 LeonardSSXiaCJiangBHStinefeltBKlandorfHHarrisGKet al

Moreover, calcium supplementation has been shown to aid in weight loss in obese humans consuming a calorie-deficient diet (142) and in calorie-restricted obese mice (111), and has also been reported to inhibit weight regain during refeeding in mice (122)

However, taking coffee by mouth may be safer and more effective : blood caffeine levels were 3.5x higher after drinking coffee than after an enema in a trial on 11 people [35+, 36, 37, 38, 39, 40, 41, 42, 43, 44]

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Immunology 171 (3), 365376 (2024)