doi: 10.4049/jimmunol.181.3.2134 17 OgataAFChengCADesjardinsMSenussiYShermanACPowellMet al
Rosen AD, Robertson KD, Hlady RA, Muench C, Lee J, Philibert R, et al
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The anti-arthritic effect of cardamomin has been evaluated in a rheumatoid arthritis (RA)-induced rat model, specifically on the pain and inflammatory response of RA
after stimulation of SMase-dependent ceramide formation, assembly of the death-inducing signaling complex (DISC) and oligomerization of Fas receptor, as well as cleaved caspase-8 and caspase-3, were detected [130]
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