Meirade-Faria FBednarskaOStromMSoderholmJDWalterSAKeitaAV
Toll-like receptor 5 (TLR5), the PRR which recognizes flagellin on the epithelial surface, is also involved in the maintenance of gut microbiota homeostasis
That is a plausible site-targeting strategy
Actionable Takeaway Routinely screen patients experiencing prolonged social isolation or bereavement for irritability, aggression, and anxiety, and implement structured social reconnection strategies (e.g., group therapy, regular follow-ups, community engagement) to mitigate these biologically primed risk states
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Its primary job is to protect your cells from oxidative stress