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[111] The microbiological assay has been the most commonly used assay technique for foods, utilizing certain vitamin B 12 -requiring microorganisms, such as Lactobacillus delbrueckii subsp
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Women who do not get enough vitamin B12 may have a higher risk of giving birth to a baby with a potentially disabling or fatal birth defect.
[36] [37] [38] A long-term study where vitamin B 12 was supplemented across a period of 10 years, led to lower levels of weight gain in overweight or obese individuals (p 20% of elderly individuals showed evidence of marginal vitamin B 12 depletion (serum vitamin B 12 : 148221 pmol/L)
The body readily converts cyanocobalamin to active forms through normal metabolic pathways, so bioavailability differences between B12 forms are minimal in individuals with intact conversion capacity
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