glutathione conjugation phase 2 II Drug Metabolism The Multifaceted Role of Glutathione

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Jingjing Huang, Ghent University, Belgium Updates Copyright 2022 de Bont, Donnay, Couturier and Rouhier

mGluR5 acts as an important cofactor, its chronic activation can enhance NMDA receptors (NMDARs) activity and further amplify neuronal excitotoxicity [37]

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This effect was accompanied by a significant upregulation of SIRT1 expression