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Concurrently, inflammation-induced impairment of iron efflux exacerbates iron retention

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In addition to treating dementia, the HGF mimics of the invention may be used for neuroprotection and/or to treat neurodegenerative diseases, some of which also involve dementia as described above

Ruscoe et al., 2001

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HMGB1 neutralization also decreased bacterial translocation from the gut during APAP hepatotoxicity [160]