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Selected Preclinical Data Study 1: Genetic Proof-of-Concept A seminal investigation reported elevated NNMT expression in white adipose tissue (WAT) and liver of obese/diabetic mice
A quinolinium-based, selective NNMT inhibitor used to interrogate NNMT biology in cells and animal models of obesity, insulin resistance, and related metabolic phenotypes (commonly as the iodide salt
Biochemical Journal , 467(2), 289301
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As aforementioned, these neurotransmitters are involved in appetite regulation
THESE CHEMICALS ARE NOT INTENDED TO BE USED AND SHOULD NOT BE USED IN INAPPROPRIATE APPLICATIONS, SUCH AS, WITHOUT LIMITATION, FOOD ADDITIVES, DRUGS, COSMETICS, HOUSEHOLD CHEMICALS, OR OTHER APPLICATIONS OUTSIDE OF IN-VITRO LABORATORY RESEARCH, PRE-CLINICAL RESEARCH, OR IN LABORATORY CHEMICAL SYNTHESIS OR TESTING OF DIFFERENT MATERIALS
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