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The Premature Infant Pain Profile score (PIPP score) was lower in 30 infants treated with common sedation plus melatonin during intubation and mechanical ventilation than in those treated with common therapy alone 115

Excess copper catalyzes protein disulfide bond formation in the bacterial periplasm but not in the cytoplasm

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This indicates that the Grx activity, presumably catalyzed by the N-terminal Grx domain of the enzyme [11], could be dissociated from the other activities of the enzyme, which should be catalyzed by the C-terminal GCUG motif

& Control (2013)