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Preclinical models report accelerated structural restoration following peptide exposure, characterized by increased fibroblast proliferation, enhanced extracellular matrix organization, and improved collagen deposition

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doi: 10.1007/S00125-005-0042-1 66 van TienhovenRVuANKaddisJSRoepBO

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The combination may amplify gastrointestinal discomfort in susceptible individuals, though this represents an additive effect rather than a true pharmacological interaction