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Cataldo et al., 2020b)

McConnachie LA, Mohar I, Hudson FN, et al

10.1038/373699a0 Nature 161 SchultzJ

However, the kinetic patterns do not support a ping-pong mechanism and the nonenzymatic first reaction with a second order rate constant of 0.6 M 1 s 1 is too slow to explain the rapid turnover 3,12,14,15,30

They found negative correlations between clinical symptom scores and metabolites involved in redox metabolism, as well as neurotransmitters in patients treated with sulforaphane