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However, this function can be compromised during copper overload, as Cu binding to the cysteine residues of GPX4 promotes its ubiquitination and autophagic degradation, thereby disrupting lipid peroxide metabolism and sensitizing cells to ferroptosis [65]

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doi: 10.1016/j.redox.2020.101674 39 Abdal DayemAHossainMKLeeSBKimKSahaSKYangGMet al

Km theo kem dng m: Khi t hnh l, hy dnh mt chai kem dng c ch s bo v SPF va phi, kt hp vi vin L-Glutathione duy tr m v sng cho da