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Post-surgical recovery affecting multiple tissue types, chronic widespread inflammation, and patients whose primary complaint is global stiffness and reduced range of motion that has not improved with localized treatment all fit the TB-500 indication

[5] [7] At dosages exceeding 5 grams, there is a potential risk for more severe adverse effects, including renal dysfunction, blood toxicity, and neurological symptoms

Routine thyroid monitoring is not required in users without risk factors

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The Pernicious Anaemia Society notes this is recognised but not fully understood

This can lead to a deficiency in Complex II of the mitochondrial electron transport chain, which generates reactive oxygen species (ROS)