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Shoulder injections are intended to not only be therapeutic but also are very useful in diagnostic terms

10.1097/BRS.0b013e3181b26ed1

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The biological effects downstream of cAMP elevation have been previously demonstrated to be predominately mediated by cAMP-dependent protein kinase (PKA), which phosphorylates cAMP-response element (CRE) binding protein (CREB) (21)

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