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Additionally, abnormal amino acid metabolism exacerbates pancreatic injury through multiple pathways, including impaired cell repair, increased oxidative stress, and immune dysfunction (68)

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Interestingly, estrogen receptors ER and ER are located in the axons and synaptic terminals of pre-synaptic cells and also in the dendritic spines (structures crucial for synaptic transmission) of post-synaptic cells (Zarate et al., 2017)

291 Additionally, VSMC transdifferentiation and apoptosis are common pathogenic mechanisms in aortic aneurysm/dissection and are associated with lactylation

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& Vercruysse, J