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Example experimental endpoints: healing rate (time to closure), expression of repair markers (e.g., collagen I/III ratio), and functional recovery assays

Organoids have been successfully developed from EC primary tumor samples of a spectrum of clinical types, ranging from hyperplasia to low- and high-grade cancer [64, 69]

doi: 10.1016/J.JFF.2013.02.008 89 YounHSLeeJYSaitohSIMiyakeKKangKWChoiYJet al