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Mitofusin-2 induced by exercise modifies lipid droplet-mitochondria communication, promoting fatty acid oxidation in male mice with NAFLD

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The NLRP3 inflammasome is activated in brain leukocytes (i.e., microglia) by peripheral inflammatory stimuli, thus creating an inflammatory response in the CNS that mirrors peripheral inflammation, marked by increased IL-1 [79, 80]

Sci Rep 2019;9:4060