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The sudden release of toxins can overwhelm the kidney and livers ability to eliminate them, leading to an inflammatory response that manifests as a worsening of symptoms

Nature Reviews Endocrinology, 9 (6), 357-365

The exact mechanism of peptides acting as antioxidants is not clearly known but some aromatic amino acids and histidine are reported to play an important role in the antioxidant activity

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The data revealed that patients taking greater than 600 mg/day of NAC reported a 45.8% significant positive effect on their symptoms, while direct glutathione administration yielded a 42.4% significant positive response rate, highlighting the critical importance of the redox pathway in symptom management

Laboratory studies demonstrate that vitamin D metabolites enhance antimicrobial peptide production, modulate inflammatory responses, and support regulatory T-cell function