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Expectedly, depletion of cystine or inhibition of the Xc- antiporter using synthetic small molecule inhibitors including erastin, sulfasalazine, sorafenib and even excess of glutamate triggered cystine depletion, decreased GSH level and reduced GPX4 activity, culminating in ferroptosis induction

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Gubbels Bupp MR, Jorgensen TN

Strengthens the Immune System As an immune modulator, glutathione enhances the bodys defense mechanisms

This indicates that NKCC1 regulates MMP expression via the Wnt/-catenin signaling pathway, thereby affecting cell invasion (84)

Linker et al., 2002