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Furthermore, the effect of LA (50mg/kg or 100mg/kg) on healthy animals was evaluated in the preliminary experiment, and no changes of renal morphology and function were found in the healthy mice after oral medications of LA (shown in Supplementary Figure 1)

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While topical application of glutathione may not be as potent as injections or oral supplements, these products can still provide gradual lightening effects and improve overall skin tone

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