Huang H, Chen K, Zhu Y, Hu Z, Wang Y, Chen J, et al
Mathematical Framework for Human Equivalent Dose The human equivalent dose (HED) formula is: HED (mg/kg) = Animal dose (mg/kg) (Animal Km / Human Km) Standard Km constants used in pharmacological scaling are: Rat Km = 6 Human Km = 37 To illustrate: If a rat study administers 10 mcg/kg, convert micrograms to milligrams: 10 mcg = 0.01 mg HED = 0.01 (6 / 37) HED 0.00162 mg/kg HED 1.62 mcg/kg For a 70 kg individual: 70 1.62 mcg 113 mcg This represents a mathematically scaled equivalent exposurenot a prescription
References GHK-Cu Peptide Canada Quality Assurance Verified products of GHK-Cu peptide Canada from Maple Research Labs undergoes independent third-party HPLC analysis confirming purity exceeding 99%+
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[DOI] [PubMed] [Google Scholar] 81.Hennet T., Peterhans E., Stocker R
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