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In some embodiments, the otic formulation or composition comprises between about 0.01% to about 20% by weight of the viscosity modulating agent(s)

The reasons for these changes, apart from excess ROS leading to increased GSH depletion in cardiomyocytes, are disturbances in the anabolic process of GSH, causing a further decrease in intracellular GSH content

[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Parker W., Hornik C.D., Bilbo S., Holzknecht Z.E., Gentry L., Rao R., Lin S.S., Herbert M.R., Nevison C.D

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