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More pack-years are associated with a higher risk of lung disease.

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In this paper we use data from the National Health and Nutrition Examination Survey (NHANES) and hierarchical (i.e., individuals are grouped within birth cohorts and time periods) ageperiodcohort (HAPC) analysis to examine lifecycle (i.e., age), historical (i.e., period), and generational (i.e., cohort) distribution of smoking among American adults over the last five decades 5