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10.1016/j.bpj.2011.06.014 43 GhyselsA.KrmerA.VenableR

J Cell Physiol (1989) 141(1):405

Retrieved 11 October 2015

According to the authors, boosting GSH status beneficially upregulates the genes of VD metabolism and VDR, both of which are needed to increase the bioavailability and blood levels of 25(OH)VD and reduce inflammation levels. They also found that co-supplementation with vitamin D and L-cysteine resulted in the upregulation of vitamin D regulatory genes and boosted vitamin D levels in the blood, as well as reduced inflammation and insulin resistance each with higher success compared to supplementing with vitamin D alone

6.6 Glutathione-S-transferase (GST) GSTs activities lead to the labelling of various xenobiotics for vacuolar sequestration or transfer to apoplast by catalysing their conjugation with electrophilic centres and nucleophilic tripeptide GSH [199]

In September 2023, the FDA listed BPC-157 as a Category 2 bulk drug substance