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More serious deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes

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Research shows the compounds direct effect on circadian gene expression can help scientists understand how temporal metabolic regulation affects overall health

Per ICD-10-CM Guideline I.A.15, a causal relationship between diabetes and neuropathy is presumed when both conditions are documented but the physician must still document diabetic neuropathy or explicitly state the relationship