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Although early research results appear encouraging, Retatrutide remains an investigational therapy

It highlights vagal nerve stimulations ability to downregulate the NLRP3 inflammasome, the need to individualize drugs and peptides, and the centrality of vascular tone/perfusion and mitochondrial function to healthy aging

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Stupnisek et al., 2012, 2015

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In transgenic FVB/N mice overexpressing the human HER-2/neu (erbB-2) oncogene, Epithalon administration results in a significant reduction in HER-2/neu mRNA levels, with a reported 3.7-fold decrease relative to saline controls