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doi: 10.1007/s13181-010-0071-0

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The ChaC family (ChaC1 and ChaC2, cytoplasmic glutathione-specific -glutamyl cyclotransferases) has recently been shown to take part in GSH metabolism

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In one study [56] investigating the impact of NAC on noise-induced hearing loss in men ( n = 53) taking 1200 mg per day for 14 days led to a significant reduction of noise-induced temporary threshold shift, or the amount of hearing loss after a period of heightened noise exposure in a work setting relative to baseline, or pre-shift levels