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PINK1/Parkin-dependent mitophagy efficiency decreases, the RAB7/CCZ1-MON1 complex activity is impaired, and autophagosome formation may be blocked, resulting in continued accumulation of damaged mitochondria and protein aggregates [130]

Glutathion spielt eine entscheidende Rolle bei der Reduzierung oxidativen Stresses, und ein Mangel daran kann das Risiko fr chronische Erkrankungen wie Herz-Kreislauf-Erkrankungen und Hepatitis erhhen

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1.16 Variants of hashimotos thyroiditis There are other variations of HT besides the traditional form

However, ferroptosis suppressor protein 1 (FSP1) has an inhibitory effect on ferroptosis by reducing CoQ10, inhibiting lipid peroxidation and ferroptosis terminal driver pLPO