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Followed by weekly, then monthly maintenance doses
Reassuring yourself the effects are temporary as your body adjusts
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
AOD-9604 stimulates lipolysis, which is the breakdown of fat, and inhibits lipogenesis, the process that transforms non-fat food materials into body fat
While toxicity is rare, excessive intake of certain B vitamins (particularly B or B) from multiple sources could increase the risk of side effects (like niacin flush or peripheral neuropathy)
