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Methods We examined the general health check-up data and claim database of the Korean National Health Insurance Service (NHIS) of 2,668,615 participants with type 2 diabetes mellitus who had examinations between 2009 and 2012

Wang, Y.-T

Circulating IGF-1 levels vary depending on the persons age: there is initially an increase in serum IGF-1 from birth to puberty, followed by a stable decline with age in response to the lower GH levels [9,10]

Tissue Barriers 1 , e24997 (2013)

Excessive ROS generation interferes with insulin signaling by impairing insulin receptor substrate phosphorylation and promoting inflammatory kinase activation, thereby favoring insulin resistance

One patient showed continued shortening of glands