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As far as DON was concerned, even though it could induce a significant dose-dependent decrease in the levels of proteins, mRNA, IgM, IgG, IFN-, IL-10, IL-6, IL-4, and IL-2, its simultaneous administration with Se resulted in a significant increase in the levels of all factors studied, including proteins and mRNA

The prohibition applies both in-competition and out-of-competition

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Arena U, Stasi C, Mannoni A, Benucci M, Maddali-Bongi S, Cammelli D, Assarat A, Marra F, Pinzani M (2012) Liver stiffness correlates with methotrexate cumulative dose in patients with rheumatoid arthritis

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doi:10.1093/humrep/des319