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Description

Cecal samples Cecal weight was measured since the weight of this portion of the intestine appears to be highly influenced by the microbiome (e.g., certain antibiotic treatments dramatically increase cecal weight 27,28,29,30,31 but not the colon 27 )

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Confirmatory secondary endpoints included 20%, 25%, and 30% weight loss, with all analyses performed on an intention-to-treat basis and reported with 95% confidence intervals