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The two systems operate in parallel rather than competing, which is why combining them can produce greater weight loss than either alone

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Understanding Melanin and Skin Pigmentation Before we can understand how glutathione works, we have to look at what gives our skin its color

The researchers on this paper speculated that thymoquinone, or TQ, the primary active constituent of [BSO], may have been primarily responsible for the effect because TQ protects cells against oxidative damage induced by a variety of free radical-generating pathologies, and it also stimulates the production of acetylcholine, which causes the release of melanin and darkening of the skin through stimulation of cholinergic receptors

PMID: 6173142

We found that, for SNP rs179982 (gene CPT2 ), patients with GG genotype had lower plasma L-Cn levels than those with AA genotype ( Figure 5A )