Nasal drug deliverypossibilities, problems, and solutions. Journal of Controlled Release , 2003
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The Sucrosomial B12 formulation possibly overcomes these obstacles by entrapping vitamin B12 within a protective matrix composed of phospholipids, primarily derived from sunflower lecithin, and a sucrester (sucrose ester)
Much of the peptide can be destroyed before it ever reaches the intestines where it could be absorbed
