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Experimental in vivo and in vitro models of multiple sclerosis: EAE and beyond

DET1 serves as a structural scaffold, bridging COP1 and Ube2e2 to initiate potential ubiquitin addition on substrates, while DDB1 recruits the CULLIN4-RBX1 complex to facilitate Ube2d3-mediated ubiquitin chain elongation

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Additionally, certain NPs may function as nanocarriers, transporting drugs for PD on their surfaces, thereby facilitating the controlled and prolonged release of therapeutic agents

Effect of glibenclamide on pancreatic hormone release from isolated perifused islets of normal and cysteamine-treated rats