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204,270,615,616 Indeed, more recent studies reveal that this NiCo class of metal-responsive riboswitches is overrepresented in obligate anaerobes and has recently been shown to exhibit a robust response to Fe II (but not Fe III ), a conclusion reached through use of a fluorescent-sensing derivative of the NiCo riboswitch

This stability sets it apart from many other peptides used in laboratory research, making it a highly practical candidate for a wide range of experimental protocols